This list is a compilation of our personal favorites, reader recommendations, and top sellers from the Facentials store to make a list for the Top 10 Best Probiotics reviewed in 2021.
Today there are hundreds of Probiotics to choose from. And we know how there are different factors people judge a product on.
So, after researching dozens and dozens of them, we were able to break them down to our Top 10 Best Probiotics in 2021.
*Note*: The content below is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.
- 🥇Top 10 Best Probiotics in 2021
- 1. MaryRuth Organics Liquid Plant-Based Probiotics
- 2. Royal-Organica Dr. Ian Stern Formulated Probiotics
- 3. LiveWell Labs Nutrition Clinical Grade Probiotics
- 4. Dr. Mercola Complete Probiotics
- 5. Vita Miracle Ultra-30 Probiotics
- 6. Douglas Laboratories Probiotics
- 7. NatureWise Time-Release Probiotics
- 8. Intelligent Labs Probiotics
- 9. Naturelo 50 Billion CFU Probiotics
- 10. Vitamin Bounty Pro 50 Probiotics
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🥇Top 10 Best Probiotics in 2021
MaryRuth Organics Liquid Plant-Based Probiotics
Royal-Organica Dr. Ian Stern Formulated Probiotics
LiveWell Labs Nutrition Clinical Grade Probiotics
Dr. Mercola Complete Probiotics
Vita Miracle Ultra-30 Probiotics
Douglas Laboratories Probiotics
NatureWise Time-Release Probiotics
Intelligent Labs Probiotics
Naturelo 50 Billion CFU Probiotics
Vitamin Bounty Pro 50 Probiotics
1. MaryRuth Organics Liquid Plant-Based Probiotics
Features & Benefits
- Over 1,450+ Positive Reviews
- 100% ORGANIC, 100% Raw, Non-GMO, Vegan, Paleo, Ketogenic, Gluten Free, Wheat Free, Corn Free, Soy Free, Nut Free. Bariatric and Celiac Friendly.
- SUPPORTS IMMUNITY and effective to use with weight maintenance programs. Supports Digestive Problems: Constipation, Diarrhea, Gas, Bloating, IBS and other gastrointestinal complaints.
- FORMULATED BY Certified Health Educator, Nutritional Consultant, Culinary Chef MaryRuth Ghiyam. #1 Best Selling Liquid Probiotics Nationwide. Made in a GMP compliant facility in a 4oz GLASS BOTTLE. Mother-daughter owned company.
"I have many medical conditions which can cause problems with my digestion such as acid reflux. I spoke with a person in the supplements section of the local store. He mentioned I should not have acid reflux as this age and to try a specific probiotic. Well...I had already purchased MaryRuth Organics Probiotic which seemed to be quite similar to the one that was recommended. It has been almost three weeks taking it. I noticed within the first few days the acid reflux calmed down considerably. By the second week, I was able to eat meals with chili powder and some wheat. I am hoping to try tomatoes in another week or so. I have IBS as well and I seem to be getting regular as each day goes by. I am only taking 30 - 40 drops (it is very effective) and it does not have to be refrigerated which is awesome. I am in no way stating that people who have stomach issues will be cured or can eat what they want. This is ONLY my experience. But if you do have digestive issues it is worth looking into getting a good probiotic." - freesia3
2. Royal-Organica Dr. Ian Stern Formulated Probiotics
Features & Benefits
- Over 300+ Positive Reviews
- YOUR SEARCH FOR THE MOST EFFECTIVE PROBIOTIC SUPPLEMENT IS COMPLETE- Many other probiotic supplements promise the world but fail to deliver results. It only takes one look at the ingredients to understand why. To feel your best, you need the most potent ingredients with none of the harmful additives or fillers. That is why we tirelessly worked for years until we found a formula that not only delivers results, but also we are proud to take ourselves and give to our families.
- YOU DON’T HAVE TO SETTLE FOR JUST A “GOOD” PROBIOTIC- You don’t settle in other areas of your life so why settle here? Our formula is the most complete one on the market today with 12 of the most effective, clinically-proven probiotic strains, an organic prebiotic, and L-Glutamine to increase absorption and repair "leaky gut". 100% plant-based veggie capsules reduce oxidation and keep more bacteria alive. People may not be perfect but this formula is.
- “PERFECT” MEANS ZERO ADDITIVES OR ALLERGENS- That’s right. We said Zero. Not “only a few”, or “as little as possible”. Zero. Zilch. Nada. No animal products, no fillers, no GMOs, no soy, no gluten, no additives of any kind. Our commitment to excellence extends to our manufacturing process as well. Rebalance is made right here in the US under strict GMP guidelines and kept in a climate-controlled facility to keep all the bacteria alive and potent.
"I was feeling really run down from stress and really struggling for energy and needed something to boost up my immune system so I was recommended this by a good friend. I had been in the market for a while for a good probiotic and hadn't found any both for me and my mom who has GI issues and is elderly. In less than a week after taking this, I wasn't just back to myself, but rather much better than my previous self. I have more spring in my step and just feel way better overall with much more energy. This is a great product. I will use it for the rest of my life and urge everyone else to do so as well. Don't hesitate! Buy it!" - Joseph Riggio
3. LiveWell Labs Nutrition Clinical Grade Probiotics
Features & Benefits
- Over 938+ Positive Reviews
- 45 Billion CFU Strength: Probiotics for women and men featuring 45-billion guaranteed live cultures and 11 clinically studied probiotic strains, per capsule! Includes NutraFlora Prebiotic Fiber to boost the growth of good gut flora and support overall gut health.
- Dairy, Gluten, Soy, Preservative FREE: Each delay-release capsule is also non-GMO, certified vegan, made in America and does not require refrigeration.
- Bloat Relief: Backed by science. Bye, bye muffin top, hello safe and effective cleansing.
- Digestive + Immune Support: Our doctor-formulated probiotics establish and maintain favorable intestinal flora which is key for healthy digestion, bloat relief, constipation, leaky gut, weight loss and more.
"Not joking, this product really works and immediately. I was going through a kind of digestive disorder for about 2 consecutives months. I knew my gut were not working normal. Having constant diarrea, gut cramps, bloated, slow digestion, hemorroids and even my lips were getting cracked. I knew my gut flora was not on it's best and reason could be, antibiotics, protein shakes that I was not used to. After 1st week taking this probiotic, literally everything disapear and has not come back since then. I also have to mention that I used active 99% Aloe Vera juice too." - Juan A.
4. Dr. Mercola Complete Probiotics
Features & Benefits
- Over 665+ Positive Reviews
- Each Bottle of Complete Probiotics (70 Billion CFU) Contains 30 Servings
- Following Dr. Mercola’s belief in providing the best quality products, this product is GMO Free, Gluten Free, and Soy Free.
- Complete Probiotics Promotes optimal growth of healthy bacteria, and provides support for your immune health.
- Our Complete Probiotics offers 10 different probiotic strains, and demonstrates high potency through independent laboratory tests
"I've used probiotics for years and I've cycled through quite a few brands before I found this one. Both my partner and I have had our gall bladders removed and my partner has microscopic colitis, so probiotics are rather important. Other probiotics made our bodies rather "yeasty" (skin feeling tacky under arms, etc) but this probiotic does not do that at all. As far as bowel movements, we've been as regular as regular can be. We've found that we do not need to even take the recommended dosage. The directions say to use one pill daily ... but we use just four a week and are on a schedule of SUN/TUE/THUR/SAT which works perfectly for us. Anyway, we highly recommend it. It's definitely the best that we've used." - Brad S. - Austin, TX
5. Vita Miracle Ultra-30 Probiotics
Features & Benefits
- Over 880+ Positive Reviews
- 20X MORE EFFECTIVE THAN TABLETS AND PEARLS which get partially digested in the stomach and kill the bacteria before it can reach the intestines where it does it’s work. Vita Miracle patented Probiotics Supplements allow the live culture probiotics to live past the harsh stomach acid and into the intestines where they can thrive
- GUARANTEED SHELF LIFE PLUS THE BEST PROBIOTICS SUPPLEMENT ON AMAZON WITH 18 STRAINS of (GOOD GUY) BACTERIA (Almost twice the # of strains and 2 to 6 times the number of cfu's over the nearest competitors mens or womens probiotic) - Our highest potency probiotics for women men teens and kids is the most complete probiotics pills with prebiotics on Amazon or anywhere
- IMPROVE YOUR OVERALL HEALTH - Most Womens Probiotics with prebiotic don't address Poor overall Health, immune system, and low energy levels due to the gut not absorbing nutrition essentials like vitamins and minerals properly into your body. ULTRA-30 Probiotics For Men - will improve both mens and womens gut health and allow you to get back to your happy energetic self
"I researched probiotics on the market for quite some time. I discovered after extensive research that this is the best product on the market to purchase, so I bought it. My doctors have agreed that I can take it after they also looked into it. For the first time in awhile I am able to lose weight and feel no bloating. My stomach is flatter and I feel so much better after gong on this Probiotic. IF IT WAS POSSIBLE TO GIVE IT 10 STARS, I WOULD!" - Kelly
6. Douglas Laboratories Probiotics
Features & Benefits
- Over 72+ Positive Reviews
- ALSO CONTAINS PREBIOTICS: also included in the synbiotic blend, is NutraFlora scFOS prebiotic fiber that is well tolerated and works synergistically with probiotics to flourish in the intestinal tract.
- DIGESTIVE & IMMUNE HEALTH: Helps to support digestive health, nutrient absorption, and immune health by balancing intestinal microflora.
- DIGESTIVE: Dietary supplement formulated to support G.I. health and its highly complex ecosystem.
- DOUGLAS LABORATORIES researches, develops and manufactures the right suite of rigorously designed, science-based, healthy aging supplements. With a 60-year heritage of innovating and designing nutritional products, we push the potential of active individuals to continually perform at their personal best.
"It’s not the cheapest probiotic, but it is very effective. I have a microflora that is very sensitive to different foods and medicine, so if I don’t take probiotic sometimes I have stomach pain every day. I go to a restaurant and I have to leave as it becomes unbearable and I leave home to lay down and wait for the gas to naturally leave my body if it so pleases. Second day after I started taking this, the pain was gone, just like that. Have not had it ever since (it’s the 3rd month of me taking this). It’s well worth me being able to live a normal life. If you have a similar problem, get it!" - saleh
7. NatureWise Time-Release Probiotics
Features & Benefits
- Over 997+ Positive Reviews
- SUPERIOR SURVIVABILITY: It's not the CFU you start with that matters, it's the CFU you end up with! Over 95% of standard probiotic capsules don't make it to your gut alive. Our Wisebiotics advanced caplet technology delivers 15x more live, active cultures safely to your gut, making our Maximum Care formula with 30 billion CFU as effective as a 450 billion CFU standard probiotic!*
- STRENGTH IN DIVERSITY: Our maximum strength formula replenishes your gut flora with a diverse blend of prebiotics and probiotics, including 30 clinically researched strains, 30 billion CFU strong to support your digestive and immune health.*
- CONTROLLED TIME RELEASE: Our unique Wisebiotics delivery system protects probiotic flora from stomach acids and distributes live cultures throughout your intestines in a controlled time release over 8-10 hours — a benefit that no standard probiotic capsules can match.*
"After having a Full-Knee replacement , twice over a two year period and having been prescribed Oxycontin , per codon, and Vicadon during the two years plus ,this "Destroyed" my Digestive track wiped out all the good strains and the bad bacteria from the Opiates took over and I was no longer "Regular in Daily Elimination" and have suffered since the to find regularity and comfort trying many different brands of Probiotics and finding no success or relief , having heard and reading about "Naturewise" I bought the Time-Released Maximum Care and I can honestly say , I have No upset stomach, or discomfort and the Happiness that comes with Regularity is back ....This is the TRUE ANSWER to those as myself in TROUBLE WITH YOUR GI TRACK ....NATUREWISE IS REAL, AND WORKS." - Rodney Andregg
8. Intelligent Labs Probiotics
Features & Benefits
- Over 179+ Positive Reviews
- HEAL YOUR BODY AND SUPERCHARGE YOUR HEALTH: 80% of you immune system is located in the gut, and the gut microbiota influences virtually every aspect of health. Modern diets, stress and pollution all hit our gut hard which is why we need probiotics, but only the highest quality, strongest and best strains will make a difference. Cheap and low quality Probiotics won’t help you.
- We’ve created the strongest and most effective probiotic around. Each capsule contains a minimum of 50 CFU when you take it, because all probiotics degrade over time. This is unlike other brands who only fill to 50B, and then their strength quickly decreases.
- All 10 of our probiotic strains are patented and sourced through DuPont Danisco. All are specific acid and bile resistant strains to ensure they reach your gut to grow and reproduce. Also to guarantee the 50 billion CFU strength we use Activ-Polymer bottles and an Oxyfree desiccant to ensure our probiotics stay virtually moisture free and reduce oxygen levels in the bottle to only 0.01%.
"I searched for an effective probiotic, after many months of taking a large National Supplement Chain's labeled brand...I didn't feel as if I was reaping the benefits and results I had hoped for... it seemed I was still experiencing bloating, contstipation and irregularity...(I practice eating a very clean diet daily)
I looked on Amazon and searched brands and checked reviews. Decided to try Intelligent Labs Probiotic..I was contacted by company after placing order..never has happened to me after placing an online order for anything!..after a couple of weeks taking this probiotic, I seem to have had positive results, although it has taken a bit of time for my body to adjust to the increase in CFUs..I also received a follow up email from this family owned business, making sure I received peoduct and double checking with me in the event I had questions or concerns....again has NEVER happened after an online purchase!
I would recommend Intelligent Labs for all supplement needs.." - Janet Adkins
9. Naturelo 50 Billion CFU Probiotics
Features & Benefits
- Over 144+ Positive Reviews
- Promotes Growth of Healthy Gut Bacteria
- Non-GMO. Gluten Free. Soy Free. Yeast Free. Dairy Free. 100% Natural. Vegan. Vegetarian. Made in USA
- Provides Relief for Constipation, Diarrhea, Candida Infection, IBS, Bloating, and Gas.
"As a student in my PhD program in natural medicine I was always taught the phrase by Hippocrates that 'disease begins in the gut'. After studying nutrition and natural health over the last 26 years that never rings more true than today. This is an excellent probiotic with 50 billion CFU and 11 different strains. With 2/3 of our immune system in our GI tract it is so important to make sure we keep it healthy and happy with fermented foods and probiotics. I like this brand because it is shelf stable and I know all the other products from Naturelo have been a grand slam." - Wellfit
10. Vitamin Bounty Pro 50 Probiotics
Features & Benefits
- Over 4,187+ Positive Reviews
- Vitamin Bounty's Pro 50 offers an potent, 50 Billion organisms per serving, making it one of the most effective probiotics with prebiotics on the market.
- Unlike other probiotics that only contain 1 or 2 strains of probiotic strains, Pro-50 has 13 probiotic strains, ensuring you will get the support you need for your overall digestive health.
- Pro-50 uses a patented delayed release capsule, that protects the live organisms in the capsule from stomach acid, delivering more cultures and ensuring maximum efficacy.
- The capsule itself is a delayed-release vegetable capsule, with prebiotic greens included. developed and tested in a NSF certified facility. The potency and purity is guaranteed.
"I be never tried a probiotics before, but I can tell you, this product is SERIOUSLY AMAZING!! Ive had Fibromyalgia for over 20 years. Living in constant pain, fatigue, brain fog, etc. I've seen every kind of doctor and they ALL kept pushing Western medicine, since the beginning. Things like,... steroids, STRONG pain meds (opioids) several antidepressants, anxiety (benzodiazepines) and the list goes on & on.... I literally felt like my life was over!! I was in bed most days & just watching my once, HEALTHY & ACTIVE lifestyle fade away. I had just given up!! I felt like I'd done EVERYTHING humanly possible to try & figure out how to heal myself. NEVER did a doctor ask me about my GUT health. A friend of mine asked me if I'd tried a probiotic. I couldn't afford a Holistic specialist (most insurance doesn't cover that) but, I started looking online about gut health and decided to give a high quality probiotic a try. I started taking Vitamin Bounty pro 50 and I didn't expect anything to change since I'd already accepted the fibromyalgia and sedentary life that was my 'fate' Well, A LOT has changed in just 3 weeks!!! I can honestly say that "I feel cured"!!!! I'm pain-free, have TONS of energy and sleep great! Getting the toxins out of my body IS what HAD to happen!! I feel ALIVE again!! I will say that it was a little hard 'detoxing' - sweats, chills, metal taste in my mouth, foggyness, bowel changes... but that was all worth it!! Make sure to drink PLENTY OF WATER during this time of detoxification. THANK YOU, THANK YOU, THANK YOU!!!!!!!!" - Diane